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Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn

BACKGROUND: Tau protein is the principal component of the neurofibrillary tangles found in Alzheimer's disease, where it is hyperphosphorylated on serine and threonine residues, and recently phosphotyrosine has been demonstrated. The Src-family kinase Fyn has been linked circumstantially to the...

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Detalles Bibliográficos
Autores principales: Scales, Timothy ME, Derkinderen, Pascal, Leung, Kit-Yi, Byers, Helen L, Ward, Malcolm A, Price, Caroline, Bird, Ian N, Perera, Timothy, Kellie, Stuart, Williamson, Ritchie, Anderton, Brian H, Reynolds, C Hugh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037338/
https://www.ncbi.nlm.nih.gov/pubmed/21269457
http://dx.doi.org/10.1186/1750-1326-6-12