Bim and Mcl-1 exert key roles in regulating JAK2(V617F )cell survival

BACKGROUND: The JAK2(V617F )mutation plays a major role in the pathogenesis of myeloproliferative neoplasms and is found in the vast majority of patients suffering from polycythemia vera and in roughly every second patient suffering from essential thrombocythemia or from primary myelofibrosis. The V...

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Detalles Bibliográficos
Autores principales: Rubert, Joëlle, Qian, Zhiyan, Andraos, Rita, Guthy, Daniel A, Radimerski, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037340/
https://www.ncbi.nlm.nih.gov/pubmed/21247487
http://dx.doi.org/10.1186/1471-2407-11-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037340/
https://www.ncbi.nlm.nih.gov/pubmed/21247487
http://dx.doi.org/10.1186/1471-2407-11-24

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