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Short-Lived IFN-γ Effector Responses, but Long-Lived IL-10 Memory Responses, to Malaria in an Area of Low Malaria Endemicity

Immunity to malaria is widely believed to wane in the absence of reinfection, but direct evidence for the presence or absence of durable immunological memory to malaria is limited. Here, we analysed malaria-specific CD4(+) T cell responses of individuals living in an area of low malaria transmission...

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Detalles Bibliográficos
Autores principales: Wipasa, Jiraprapa, Okell, Lucy, Sakkhachornphop, Supachai, Suphavilai, Chaisuree, Chawansuntati, Kriangkrai, Liewsaree, Witaya, Hafalla, Julius C. R., Riley, Eleanor M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037361/
https://www.ncbi.nlm.nih.gov/pubmed/21347351
http://dx.doi.org/10.1371/journal.ppat.1001281