Reactive Oxygen Species Is Essential for Cycloheximide to Sensitize Lexatumumab-Induced Apoptosis in Hepatocellular Carcinoma Cells

This study aims to investigate apoptosis induced by lexatumumab (Lexa) in hepatocellular carcinoma (HCC) cells. We assessed the sensitivity of HCC cell lines and normal human hepatocytes to Lexa and explored the sensitization of HCC cells to Lexa-induced apoptosis by cycloheximide (CHX). Our data in...

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Detalles Bibliográficos
Autores principales: Zhao, Xiangxuan, Cao, Mengde, Liu, Joy J., Zhu, Haizhen, Nelson, David R., Liu, Chen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037406/
https://www.ncbi.nlm.nih.gov/pubmed/21347335
http://dx.doi.org/10.1371/journal.pone.0016966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037406/
https://www.ncbi.nlm.nih.gov/pubmed/21347335
http://dx.doi.org/10.1371/journal.pone.0016966

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