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Phosphoinositide Regulation of Integrin Trafficking Required for Muscle Attachment and Maintenance

Muscles must maintain cell compartmentalization when remodeled during development and use. How spatially restricted adhesions are regulated with muscle remodeling is largely unexplored. We show that the myotubularin (mtm) phosphoinositide phosphatase is required for integrin-mediated myofiber attach...

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Detalles Bibliográficos
Autores principales: Ribeiro, Inês, Yuan, Lin, Tanentzapf, Guy, Dowling, James J., Kiger, Amy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037412/
https://www.ncbi.nlm.nih.gov/pubmed/21347281
http://dx.doi.org/10.1371/journal.pgen.1001295