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High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)–Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations

This note is to report how histological preparation techniques influence the extravasation pattern of the different molecular sizes of fluorescein isothiocyanate (FITC)–dextrans, typically used as markers for blood-brain barrier leakage. By using appropriate preparation methods, false negative resul...

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Detalles Bibliográficos
Autores principales: Hoffmann, Angelika, Bredno, Jörg, Wendland, Michael, Derugin, Nikita, Ohara, Peter, Wintermark, Max
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037479/
https://www.ncbi.nlm.nih.gov/pubmed/21423333
http://dx.doi.org/10.1007/s12975-010-0049-x