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Huntingtin localisation studies - a technical review
It is well recognised that there are pitfalls when defining the subcellular localisation of a protein with immunocytochemistry. Accurate protein localisation to particular cellular micro-architecture is crucial in defining its role within the cell. Huntingtin (HTT), the protein mutated in the neurod...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037564/ https://www.ncbi.nlm.nih.gov/pubmed/21339845 http://dx.doi.org/10.1371/currents.RRN1211 |