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Folding, Quality Control, and Secretion of Pancreatic Ribonuclease in Live Cells
Although bovine pancreatic RNase is one of the best characterized proteins in respect to structure and in vitro refolding, little is known about its synthesis and maturation in the endoplasmic reticulum (ER) of live cells. We expressed the RNase in live cells and analyzed its folding, quality contro...
Autores principales: | Geiger, Roger, Gautschi, Matthias, Thor, Friederike, Hayer, Arnold, Helenius, Ari |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037694/ https://www.ncbi.nlm.nih.gov/pubmed/21156800 http://dx.doi.org/10.1074/jbc.M110.171694 |
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