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Conserved generation of short products at piRNA loci

BACKGROUND: The piRNA pathway operates in animal germ lines to ensure genome integrity through retrotransposon silencing. The Piwi protein-associated small RNAs (piRNAs) guide Piwi proteins to retrotransposon transcripts, which are degraded and thereby post-transcriptionally silenced through a ping-...

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Detalles Bibliográficos
Autores principales: Berninger, Philipp, Jaskiewicz, Lukasz, Khorshid, Mohsen, Zavolan, Mihaela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037900/
https://www.ncbi.nlm.nih.gov/pubmed/21247452
http://dx.doi.org/10.1186/1471-2164-12-46