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Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B

BACKGROUND: Acid-sensing ion channels (ASICs) have a significant role in the sensation of pain and constitute an important target for the search of new antinociceptive drugs. In this work we studied the antinociceptive properties of the BM-21 extract, obtained from the sea grass Thalassia testudinum...

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Detalles Bibliográficos
Autores principales: Garateix, Anoland, Salceda, Emilio, Menéndez, Roberto, Regalado, Erik L, López, Omar, García, Teidy, Morales, Ruth A, Laguna, Abilio, Thomas, Olivier P, Soto, Enrique
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037906/
https://www.ncbi.nlm.nih.gov/pubmed/21261973
http://dx.doi.org/10.1186/1744-8069-7-10