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Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B
BACKGROUND: Acid-sensing ion channels (ASICs) have a significant role in the sensation of pain and constitute an important target for the search of new antinociceptive drugs. In this work we studied the antinociceptive properties of the BM-21 extract, obtained from the sea grass Thalassia testudinum...
Autores principales: | Garateix, Anoland, Salceda, Emilio, Menéndez, Roberto, Regalado, Erik L, López, Omar, García, Teidy, Morales, Ruth A, Laguna, Abilio, Thomas, Olivier P, Soto, Enrique |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037906/ https://www.ncbi.nlm.nih.gov/pubmed/21261973 http://dx.doi.org/10.1186/1744-8069-7-10 |
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