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Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

BACKGROUND: Parkinson's disease is a neurodegenerative disorder characterized pathologically by the loss of nigrostriatal dopamine neurons that project from the substantia nigra in the midbrain to the putamen and caudate nuclei, leading to the clinical features of bradykinesia, rigidity, and re...

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Detalles Bibliográficos
Autores principales: Bellinger, Frederick P, Bellinger, Miyoko T, Seale, Lucia A, Takemoto, Andrea S, Raman, Arjun V, Miki, Takanori, Manning-Boğ, Amy B, Berry, Marla J, White, Lon R, Ross, G Webster
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037910/
https://www.ncbi.nlm.nih.gov/pubmed/21255396
http://dx.doi.org/10.1186/1750-1326-6-8