A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses

T-cell based vaccines against HIV have the goal of limiting both transmission and disease progression by inducing broad and functionally relevant T cell responses. Moreover, polyfunctional and long-lived specific memory T cells have been associated to vaccine-induced protection. CD4(+) T cells are i...

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Detalles Bibliográficos
Autores principales: Rosa, Daniela Santoro, Ribeiro, Susan Pereira, Almeida, Rafael Ribeiro, Mairena, Eliane Conti, Postól, Edilberto, Kalil, Jorge, Cunha-Neto, Edecio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037933/
https://www.ncbi.nlm.nih.gov/pubmed/21347287
http://dx.doi.org/10.1371/journal.pone.0016921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037933/
https://www.ncbi.nlm.nih.gov/pubmed/21347287
http://dx.doi.org/10.1371/journal.pone.0016921

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