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A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses
T-cell based vaccines against HIV have the goal of limiting both transmission and disease progression by inducing broad and functionally relevant T cell responses. Moreover, polyfunctional and long-lived specific memory T cells have been associated to vaccine-induced protection. CD4(+) T cells are i...
Autores principales: | Rosa, Daniela Santoro, Ribeiro, Susan Pereira, Almeida, Rafael Ribeiro, Mairena, Eliane Conti, Postól, Edilberto, Kalil, Jorge, Cunha-Neto, Edecio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037933/ https://www.ncbi.nlm.nih.gov/pubmed/21347287 http://dx.doi.org/10.1371/journal.pone.0016921 |
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