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Upregulation of Inflammatory Genes and Downregulation of Sclerostin Gene Expression Are Key Elements in the Early Phase of Fragility Fracture Healing

BACKGROUND: Fracture healing is orchestrated by a specific set of events that culminates in the repair of bone and reachievement of its biomechanical properties. The aim of our work was to study the sequence of gene expression events involved in inflammation and bone remodeling occurring in the earl...

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Detalles Bibliográficos
Autores principales: Caetano-Lopes, Joana, Lopes, Ana, Rodrigues, Ana, Fernandes, Diana, Perpétuo, Inês P., Monjardino, Teresa, Lucas, Raquel, Monteiro, Jacinto, Konttinen, Yrjö T., Canhão, Helena, Fonseca, João E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037947/
https://www.ncbi.nlm.nih.gov/pubmed/21347301
http://dx.doi.org/10.1371/journal.pone.0016947