Cargando…
Upregulation of Inflammatory Genes and Downregulation of Sclerostin Gene Expression Are Key Elements in the Early Phase of Fragility Fracture Healing
BACKGROUND: Fracture healing is orchestrated by a specific set of events that culminates in the repair of bone and reachievement of its biomechanical properties. The aim of our work was to study the sequence of gene expression events involved in inflammation and bone remodeling occurring in the earl...
Autores principales: | Caetano-Lopes, Joana, Lopes, Ana, Rodrigues, Ana, Fernandes, Diana, Perpétuo, Inês P., Monjardino, Teresa, Lucas, Raquel, Monteiro, Jacinto, Konttinen, Yrjö T., Canhão, Helena, Fonseca, João E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037947/ https://www.ncbi.nlm.nih.gov/pubmed/21347301 http://dx.doi.org/10.1371/journal.pone.0016947 |
Ejemplares similares
-
Upregulation of inflammatory genes and downregulation of sclerostin are key elements for fracture healing
por: Caetano-Lopes, J, et al.
Publicado: (2010) -
Rheumatoid arthritis is associated with increased DKK1 expression and disturbances in the bone turnover regulating genes
por: Caetano-Lopes, Joana, et al.
Publicado: (2011) -
Chronic arthritis leads to disturbances in the bone collagen network
por: Caetano-Lopes, Joana, et al.
Publicado: (2010) -
Methotrexate and low-dose prednisolone downregulate osteoclast function by decreasing receptor activator of nuclear factor-κβ expression in monocytes from patients with early rheumatoid arthritis
por: Perpétuo, Inês Pedro, et al.
Publicado: (2017) -
Apolipoprotein E and undercaboxylated osteocalcin are associated with bone fragility but not with bone mineral density in osteoarthritis patients
por: Rodrigues, Ana, et al.
Publicado: (2011)