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Phosphorylated Dihydroceramides from Common Human Bacteria Are Recovered in Human Tissues

Novel phosphorylated dihydroceramide (PDHC) lipids produced by the periodontal pathogen Porphyromonas gingivalis include phosphoethanolamine (PE DHC) and phosphoglycerol dihydroceramides (PG DHC) lipids. These PDHC lipids mediate cellular effects through Toll-like receptor 2 (TLR2) including promoti...

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Detalles Bibliográficos
Autores principales: Nichols, Frank C., Yao, Xudong, Bajrami, Bekim, Downes, Julia, Finegold, Sydney M., Knee, Erica, Gallagher, James J., Housley, William J., Clark, Robert B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037954/
https://www.ncbi.nlm.nih.gov/pubmed/21347306
http://dx.doi.org/10.1371/journal.pone.0016771