Cargando…

Phosphorylated Dihydroceramides from Common Human Bacteria Are Recovered in Human Tissues

Novel phosphorylated dihydroceramide (PDHC) lipids produced by the periodontal pathogen Porphyromonas gingivalis include phosphoethanolamine (PE DHC) and phosphoglycerol dihydroceramides (PG DHC) lipids. These PDHC lipids mediate cellular effects through Toll-like receptor 2 (TLR2) including promoti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nichols, Frank C., Yao, Xudong, Bajrami, Bekim, Downes, Julia, Finegold, Sydney M., Knee, Erica, Gallagher, James J., Housley, William J., Clark, Robert B.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037954/ https://www.ncbi.nlm.nih.gov/pubmed/21347306 http://dx.doi.org/10.1371/journal.pone.0016771

Ejemplares similares

Dihydroceramide Desaturase Inhibition by a Cyclopropanated Dihydroceramide Analog in Cultured Keratinocytes
por: Brodesser, Susanne, et al.
Publicado: (2011)

Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology
por: Wittenbecher, C., et al.
Publicado: (2022)

Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro
por: Zarini, Simona, et al.
Publicado: (2022)

Dihydroceramides Derived from Bacteroidetes Species Sensitize TRPV1 Channels
por: Ludwig, Nora, et al.
Publicado: (2023)

Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans
por: Apostolopoulou, Maria, et al.
Publicado: (2020)

Crosstalk between dihydroceramides produced by Porphyromonas gingivalis and host lysosomal cathepsin B in the promotion of osteoclastogenesis
por: Duarte, Carolina, et al.
Publicado: (2022)

Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease
por: Yamada, Chiaki, et al.
Publicado: (2020)

Role of dihydroceramides in the progression of acute-on-chronic liver failure in rats
por: Li, Fang-Fang, et al.
Publicado: (2020)

Inhibitory effect of Porphyromonas gingivalis‐derived phosphoethanolamine dihydroceramide on acid ceramidase expression in oral squamous cells
por: Yamada, Chiaki, et al.
Publicado: (2023)

PLASMA DIHYDROCERAMIDE SPECIES ASSOCIATE WITH WAIST CIRCUMFERENCE IN MEXICAN AMERICAN FAMILIES
por: Mamtani, Manju, et al.
Publicado: (2013)

Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro
por: Siddique, Monowarul M., et al.
Publicado: (2012)

Liraglutide reduces plasma dihydroceramide levels in patients with type 2 diabetes
por: Denimal, Damien, et al.
Publicado: (2023)

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
por: Hernández-Tiedra, Sonia, et al.
Publicado: (2016)

Demographic and clinical variables affecting mid‐ to late‐life trajectories of plasma ceramide and dihydroceramide species
por: Mielke, Michelle M., et al.
Publicado: (2015)

Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds
por: Alsanafi, Mariam, et al.
Publicado: (2021)

Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production
por: Wu, Chen-Yi, et al.
Publicado: (2021)

The Antipsychotic Risperidone Alters Dihydroceramide and Ceramide Composition and Plasma Membrane Function in Leukocytes In Vitro and In Vivo
por: Canfrán-Duque, Alberto, et al.
Publicado: (2021)

Dihydroceramides in Triglyceride-Enriched VLDL Are Associated with Nonalcoholic Fatty Liver Disease Severity in Type 2 Diabetes
por: Carlier, Aurélie, et al.
Publicado: (2020)

Stage-Specific De Novo Synthesis of Very-Long-Chain Dihydroceramides Confers Dormancy to Entamoeba Parasites
por: Mi-ichi, Fumika, et al.
Publicado: (2021)

Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites
por: Dillon, Gregory M., et al.
Publicado: (2020)

The FKBP51 Inhibitor SAFit2 Restores the Pain-Relieving C16 Dihydroceramide after Nerve Injury
por: Wedel, Saskia, et al.
Publicado: (2022)

C22:0- and C24:0-dihydroceramides Confer Mixed Cytotoxicity in T-Cell Acute Lymphoblastic Leukemia Cell Lines
por: Holliday Jr., Michael W., et al.
Publicado: (2013)

The triacylglycerol, hydroxytriolein, inhibits triple negative mammary breast cancer cell proliferation through a mechanism dependent on dihydroceramide and Akt
por: Guardiola-Serrano, Francisca, et al.
Publicado: (2019)

A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
por: Noack, J, et al.
Publicado: (2014)

Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing AdipoR2
por: Ruiz, Mario, et al.
Publicado: (2021)

Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions
por: Barber, Karl W., et al.
Publicado: (2018)

Recombinant human TIM-3 ectodomain expressed in bacteria and recovered from inclusion bodies as a stable and active molecule
por: Lima, G. C., et al.
Publicado: (2023)

Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria
por: Shrestha, Amit, et al.
Publicado: (2012)

A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
por: Garnish, Sarah E., et al.
Publicado: (2023)

A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal Bacteria
por: Bao, Yiqiao, et al.
Publicado: (2021)

Recovering the susceptibility of antibiotic-resistant bacteria using photooxidative damage
por: Soares, Jennifer M., et al.
Publicado: (2023)

THE COMPARATIVE RESISTANCE OF BACTERIA AND HUMAN TISSUE CELLS TO CERTAIN COMMON ANTISEPTICS
por: Lambert, Robert A.
Publicado: (1916)

Common architecture of Tc toxins from human and insect pathogenic bacteria
por: Leidreiter, F., et al.
Publicado: (2019)

Increased tumour dihydroceramide production after Photofrin-PDT alone and improved tumour response after the combination with the ceramide analogue LCL29. Evidence from mouse squamous cell carcinomas
por: Separovic, D, et al.
Publicado: (2009)

Recovering metals from aqueous solutions by biosorption onto phosphorylated dry baker’s yeast
por: Ojima, Yoshihiro, et al.
Publicado: (2019)

Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study
por: Yang, Jieping, et al.
Publicado: (2015)

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells
por: McNaughton, Melissa, et al.
Publicado: (2016)

Cryptosporidium muris, a Rodent Pathogen, Recovered from a Human in Perú
por: Palmer, Carol J., et al.
Publicado: (2003)

Ancient human DNA recovered from a Palaeolithic pendant
por: Essel, Elena, et al.
Publicado: (2023)

Recovering The Principles of Humane Experimental Technique: The 3Rs and the Human Essence of Animal Research
por: Kirk, Robert G. W.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_b24d3104b90u1laun56ujpn30m