Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer

BACKGROUND: B-lymphoma Moloney murine leukemia virus insertion region-1 (Bmi-1) acts as an oncogene in various tumors, and its overexpression correlates with a poor outcome in several human cancers. Ectopic expression of Bmi-1 can induce epithelial-mesenchymal transition (EMT) and enhance the motili...

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Detalles Bibliográficos
Autores principales: Guo, Bao-Hong, Feng, Yan, Zhang, Rong, Xu, Li-Hua, Li, Man-Zhi, Kung, Hsiang-Fu, Song, Li-Bing, Zeng, Mu-Sheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038148/
https://www.ncbi.nlm.nih.gov/pubmed/21276221
http://dx.doi.org/10.1186/1476-4598-10-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038148/
https://www.ncbi.nlm.nih.gov/pubmed/21276221
http://dx.doi.org/10.1186/1476-4598-10-10

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