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Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures

Using a genetic model, we present a high-resolution chromatin fiber analysis of transcriptionally active (Xa) and inactive (Xi) X chromosomes packaged into euchromatin and facultative heterochromatin. Our results show that gene promoters have an open chromatin structure that is enhanced upon transcr...

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Detalles Bibliográficos
Autores principales: Naughton, Catherine, Sproul, Duncan, Hamilton, Charlotte, Gilbert, Nick
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038259/
https://www.ncbi.nlm.nih.gov/pubmed/21070966
http://dx.doi.org/10.1016/j.molcel.2010.10.013