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Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice

Human gene association studies have produced conflicting findings regarding the relationship between the 5-HT transporter (5-HTT) and anxiety. In the present study genetically modified mice were utilised to examine the effects of changes in 5-HTT expression on anxiety. In addition, the influence of...

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Detalles Bibliográficos
Autores principales: Line, Samantha J., Barkus, Christopher, Coyle, Clare, Jennings, Katie A., Deacon, Robert M., Lesch, Klaus P., Sharp, Trevor, Bannerman, David M.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038260/
https://www.ncbi.nlm.nih.gov/pubmed/20863670
http://dx.doi.org/10.1016/j.euroneuro.2010.08.005