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Linear low-dose extrapolation for noncancer health effects is the exception, not the rule

The nature of the exposure-response relationship has a profound influence on risk analyses. Several arguments have been proffered as to why all exposure-response relationships for both cancer and noncarcinogenic end-points should be assumed to be linear at low doses. We focused on three arguments th...

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Detalles Bibliográficos
Autores principales: Rhomberg, Lorenz R, Goodman, Julie E, Haber, Lynne T, Dourson, Michael, Andersen, Melvin E, Klaunig, James E, Meek, Bette, Price, Paul S, McClellan, Roger O, Cohen, Samuel M
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038594/
https://www.ncbi.nlm.nih.gov/pubmed/21226629
http://dx.doi.org/10.3109/10408444.2010.536524