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Rottlerin Inhibits Lonicera japonica-Induced Photokilling in Human Lung Cancer Cells through Cytoskeleton-Related Signaling Cascade

This study demonstrated that many apoptotic signaling pathways, such as Rho family, PKC family, MAP kinase family, and mitochondria-mediated apoptotic pathway, were triggered by Lonicera japonica extracts and irradiation in CH27 cells. Rottlerin, a PKCδ -selective inhibitor, reversed the photoactiva...

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Detalles Bibliográficos
Autores principales: You, Bang-Jau, Wu, Yang-Chang, Bao, Bo-Ying, Wu, Chi-Yu, Yang, Ya-Win, Chang, Yu-Hao, Lee, Hong-Zin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038619/
https://www.ncbi.nlm.nih.gov/pubmed/21331326
http://dx.doi.org/10.1155/2011/193842