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Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes
Huntingtin (Htt) is a membrane-associated scaffolding protein that interacts with microtubule motors as well as actin-associated adaptor molecules. We examined a role for Htt in the dynein-mediated intracellular trafficking of endosomes and lysosomes. In HeLa cells depleted of either Htt or dynein,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038646/ https://www.ncbi.nlm.nih.gov/pubmed/21169558 http://dx.doi.org/10.1091/mbc.E10-03-0233 |