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Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

Huntingtin (Htt) is a membrane-associated scaffolding protein that interacts with microtubule motors as well as actin-associated adaptor molecules. We examined a role for Htt in the dynein-mediated intracellular trafficking of endosomes and lysosomes. In HeLa cells depleted of either Htt or dynein,...

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Detalles Bibliográficos
Autores principales:	Caviston, Juliane P., Zajac, Allison L., Tokito, Mariko, Holzbaur, Erika L.F.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038646/ https://www.ncbi.nlm.nih.gov/pubmed/21169558 http://dx.doi.org/10.1091/mbc.E10-03-0233

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