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In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies

The U4/U6·U5 tri-small nuclear ribonucleoprotein particle (tri-snRNP) is an essential pre-mRNA splicing factor, which is assembled in a stepwise manner before each round of splicing. It was previously shown that the tri-snRNP is formed in Cajal bodies (CBs), but little is known about the dynamics of...

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Detalles Bibliográficos
Autores principales: Novotný, Ivan, Blažíková, Michaela, Staneˇk, David, Herman, Petr, Malinsky, Jan
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038649/
https://www.ncbi.nlm.nih.gov/pubmed/21177826
http://dx.doi.org/10.1091/mbc.E10-07-0560