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Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex

Symplekin (Pta1 in yeast) is a scaffold in the large protein complex that is required for 3′-end cleavage and polyadenylation of eukaryotic messenger RNA precursors (pre-mRNAs) 1–4, and also participates in transcription initiation and termination by RNA polymerase II (Pol II) 5,6. Symplekin mediate...

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Detalles Bibliográficos
Autores principales: Xiang, Kehui, Nagaike, Takashi, Xiang, Song, Kilic, Turgay, Beh, Maia M., Manley, James L., Tong, Liang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038789/
https://www.ncbi.nlm.nih.gov/pubmed/20861839
http://dx.doi.org/10.1038/nature09391