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Controlling the Response: Predictive Modeling of a Highly Central, Pathogen-Targeted Core Response Module in Macrophage Activation

We have investigated macrophage activation using computational analyses of a compendium of transcriptomic data covering responses to agonists of the TLR pathway, Salmonella infection, and manufactured amorphous silica nanoparticle exposure. We inferred regulatory relationship networks using this com...

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Detalles Bibliográficos
Autores principales: McDermott, Jason E., Archuleta, Michelle, Thrall, Brian D., Adkins, Joshua N., Waters, Katrina M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038849/
https://www.ncbi.nlm.nih.gov/pubmed/21339814
http://dx.doi.org/10.1371/journal.pone.0014673