Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy

BACKGROUND: The failure of cytotoxic cancer regimens to cure the most drug-resistant, well-differentiated solid tumors has been attributed to the heterogeneity of cell types that differ in their capacities for growth, differentiation, and metastases. We investigated the effect of LB1, a small molecu...

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Detalles Bibliográficos
Autores principales: Martiniova, Lucia, Lu, Jie, Chiang, Jeffrey, Bernardo, Marcelino, Lonser, Russell, Zhuang, Zhengping, Pacak, Karel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038858/
https://www.ncbi.nlm.nih.gov/pubmed/21339823
http://dx.doi.org/10.1371/journal.pone.0014678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038858/
https://www.ncbi.nlm.nih.gov/pubmed/21339823
http://dx.doi.org/10.1371/journal.pone.0014678

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