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Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy
BACKGROUND: The failure of cytotoxic cancer regimens to cure the most drug-resistant, well-differentiated solid tumors has been attributed to the heterogeneity of cell types that differ in their capacities for growth, differentiation, and metastases. We investigated the effect of LB1, a small molecu...
Autores principales: | Martiniova, Lucia, Lu, Jie, Chiang, Jeffrey, Bernardo, Marcelino, Lonser, Russell, Zhuang, Zhengping, Pacak, Karel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038858/ https://www.ncbi.nlm.nih.gov/pubmed/21339823 http://dx.doi.org/10.1371/journal.pone.0014678 |
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