D-Cbl Binding to Drk Leads to Dose-Dependent Down-Regulation of EGFR Signaling and Increases Receptor-Ligand Endocytosis

Proper control of Epidermal Growth Factor Receptor (EGFR) signaling is critical for normal development and regulated cell behaviors. Abnormal EGFR signaling is associated with tumorigenic process of various cancers. Complicated feedback networks control EGFR signaling through ligand production, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Pei-Yu, Pai, Li-Mei
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038869/
https://www.ncbi.nlm.nih.gov/pubmed/21340027
http://dx.doi.org/10.1371/journal.pone.0017097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038869/
https://www.ncbi.nlm.nih.gov/pubmed/21340027
http://dx.doi.org/10.1371/journal.pone.0017097

Ejemplares similares