Cargando…
The G(1 )phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification
Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis. Various evidence showing that oncogenes and altered tumor suppressors lead to centrosome...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038874/ https://www.ncbi.nlm.nih.gov/pubmed/21272329 http://dx.doi.org/10.1186/1747-1028-6-2 |