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The G(1 )phase Cdks regulate the centrosome cycle and mediate oncogene-dependent centrosome amplification
Because centrosome amplification generates aneuploidy and since centrosome amplification is ubiquitous in human tumors, a strong case is made for centrosome amplification being a major force in tumor biogenesis. Various evidence showing that oncogenes and altered tumor suppressors lead to centrosome...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038874/ https://www.ncbi.nlm.nih.gov/pubmed/21272329 http://dx.doi.org/10.1186/1747-1028-6-2 |