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Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms
BACKGROUND: Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both gene repression and activation. To eliminate indirect effects and examine the direct consequences of Dot1 binding and H3K79 methylation, we investigated the effects of...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038881/ https://www.ncbi.nlm.nih.gov/pubmed/21291527 http://dx.doi.org/10.1186/1756-8935-4-2 |