Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms

BACKGROUND: Methylation of histone H3 lysine 79 (H3K79) by Dot1 is highly conserved among species and has been associated with both gene repression and activation. To eliminate indirect effects and examine the direct consequences of Dot1 binding and H3K79 methylation, we investigated the effects of...

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Detalles Bibliográficos
Autores principales: Stulemeijer, Iris JE, Pike, Brietta L, Faber, Alex W, Verzijlbergen, Kitty F, van Welsem, Tibor, Frederiks, Floor, Lenstra, Tineke L, Holstege, Frank CP, Gasser, Susan M, van Leeuwen, Fred
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038881/
https://www.ncbi.nlm.nih.gov/pubmed/21291527
http://dx.doi.org/10.1186/1756-8935-4-2

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