Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses

BACKGROUND: Mutations in the Otopetrin 1 gene (Otop1) in mice and fish produce an unusual bilateral vestibular pathology that involves the absence of otoconia without hearing impairment. The encoded protein, Otop1, is the only functionally characterized member of the Otopetrin Domain Protein (ODP) f...

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Detalles Bibliográficos
Autores principales: Hurle, Belen, Marques-Bonet, Tomas, Antonacci, Francesca, Hughes, Inna, Ryan, Joseph F, Eichler, Evan E, Ornitz, David M, Green, Eric D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038909/
https://www.ncbi.nlm.nih.gov/pubmed/21261979
http://dx.doi.org/10.1186/1471-2148-11-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038909/
https://www.ncbi.nlm.nih.gov/pubmed/21261979
http://dx.doi.org/10.1186/1471-2148-11-23

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