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HIV-1 Nef increases astrocyte sensitivity towards exogenous hydrogen peroxide

BACKGROUND: HIV-1 infected individuals are under chronic exposure to reactive oxygen species (ROS) considered to be instrumental in the progression of AIDS and the development of HIV-1 associated dementia (HAD). Astrocytes support neuronal function and protect them against cytotoxic substances inclu...

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Detalles Bibliográficos
Autores principales: Masanetz, Sabine, Lehmann, Michael H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038946/
https://www.ncbi.nlm.nih.gov/pubmed/21255447
http://dx.doi.org/10.1186/1743-422X-8-35