Prevalent de novo somatic mutations in superantigen genes of mouse mammary tumor viruses in the genome of C57BL/6J mice and its potential implication in the immune system

BACKGROUND: Superantigens (SAgs) of mouse mammary tumor viruses (MMTVs) play a crucial role in T cell selection in the thymus in a T cell receptor (TCR) Vβ-specific manner and SAgs presented by B cells activate T cells in the periphery. The peripheral T cell repertoire is dynamically shaped by the s...

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Detalles Bibliográficos
Autores principales: Lee, Young-Kwan, Chiu, Sophia, Chew, Alex, Greenhalgh, David G, Cho, Kiho
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038982/
https://www.ncbi.nlm.nih.gov/pubmed/21244697
http://dx.doi.org/10.1186/1471-2172-12-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038982/
https://www.ncbi.nlm.nih.gov/pubmed/21244697
http://dx.doi.org/10.1186/1471-2172-12-5

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