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Endoplasmic Reticulum Stress Response Mediated by the PERK-eIF2α-ATF4 Pathway Is Involved in Osteoblast Differentiation Induced by BMP2

To avoid excess accumulation of unfolded proteins in the endoplasmic reticulum (ER), eukaryotic cells have signaling pathways from the ER to the cytosol or nucleus. These processes are collectively termed the ER stress response. Double stranded RNA activated protein kinase (PKR)-like endoplasmic ret...

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Detalles Bibliográficos
Autores principales: Saito, Atsushi, Ochiai, Kimiko, Kondo, Shinichi, Tsumagari, Kenji, Murakami, Tomohiko, Cavener, Douglas R., Imaizumi, Kazunori
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039352/
https://www.ncbi.nlm.nih.gov/pubmed/21135100
http://dx.doi.org/10.1074/jbc.M110.152900