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Toward the Synthesis and Biological Screening of a Cyclotetrapeptide from Marine Bacteria

The first synthesis of a naturally occurring tetrapeptide cyclo-(isoleucyl-prolyl-leucyl- alanyl) has been achieved using a solution-phase technique via coupling of dipeptide segments Boc-l-Pro-l-Leu-OH and l-Ala-l-Ile-OMe. Deprotection of the linear tetrapeptide unit and its subsequent cyclization...

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Detalles Bibliográficos
Autores principales: Dahiya, Rajiv, Gautam, Hemendra
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039471/
https://www.ncbi.nlm.nih.gov/pubmed/21339947
http://dx.doi.org/10.3390/md9010071