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O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction

BACKGROUND: The DNA repair protein O(6)-Methylguanine-DNA methyltransferase (MGMT) confers resistance to alkylating agents. Several methods have been applied to its analysis, with methylation-specific polymerase chain reaction (MSP) the most commonly used for promoter methylation study, while immuno...

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Detalles Bibliográficos
Autores principales: Brell, Marta, Ibáñez, Javier, Tortosa, Avelina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039628/
https://www.ncbi.nlm.nih.gov/pubmed/21269507
http://dx.doi.org/10.1186/1471-2407-11-35