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O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction
BACKGROUND: The DNA repair protein O(6)-Methylguanine-DNA methyltransferase (MGMT) confers resistance to alkylating agents. Several methods have been applied to its analysis, with methylation-specific polymerase chain reaction (MSP) the most commonly used for promoter methylation study, while immuno...
Autores principales: | Brell, Marta, Ibáñez, Javier, Tortosa, Avelina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039628/ https://www.ncbi.nlm.nih.gov/pubmed/21269507 http://dx.doi.org/10.1186/1471-2407-11-35 |
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