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Toxicity associated with capecitabine plus oxaliplatin in colorectal cancer before and after an institutional policy of capecitabine dose reduction

BACKGROUND: Capecitabine plus oxaliplatin (CAPOX) is an established treatment option in colorectal cancer, but can be associated with severe toxicities. METHODS: Following reporting of severe diarrhoea and dehydration with capecitabine 2000 mg m(–2) per day plus oxaliplatin every 3 weeks (CAPOX 2000...

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Detalles Bibliográficos
Autores principales: Baird, R, Biondo, A, Chhaya, V, McLachlan, J, Karpathakis, A, Rahman, S, Barbachano, Y, Cunningham, D, Chau, I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039793/
https://www.ncbi.nlm.nih.gov/pubmed/21063416
http://dx.doi.org/10.1038/sj.bjc.6605995