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Notch modulates VEGF action in endothelial cells by inducing Matrix Metalloprotease activity
BACKGROUND: In the vasculature, Notch signaling functions as a downstream effecter of Vascular Endothelial Growth Factor (VEGF) signaling. VEGF regulates sprouting angiogenesis in part by inducing and activating matrix metalloproteases (MMPs). This study sought to determine if VEGF regulation of MMP...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039832/ https://www.ncbi.nlm.nih.gov/pubmed/21349159 http://dx.doi.org/10.1186/2045-824X-3-2 |