Dectin-1 diversifies Aspergillus fumigatus–specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation

Pulmonary infection of mice with Aspergillus fumigatus induces concurrent T helper type 1 (Th1) and Th17 responses that depend on Toll-like receptor/MyD88 and Dectin-1, respectively. However, the mechanisms balancing Th1 and Th17 CD4 T cell populations during infection remain incompletely defined. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivera, Amariliz, Hohl, Tobias M., Collins, Nichole, Leiner, Ingrid, Gallegos, Alena, Saijo, Shinobu, Coward, Jesse W., Iwakura, Yoichiro, Pamer, Eric G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039849/
https://www.ncbi.nlm.nih.gov/pubmed/21242294
http://dx.doi.org/10.1084/jem.20100906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039849/
https://www.ncbi.nlm.nih.gov/pubmed/21242294
http://dx.doi.org/10.1084/jem.20100906

Ejemplares similares