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Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice

Granulocyte colony-stimulating factor (G-CSF), the prototypical mobilizing cytokine, induces hematopoietic stem and progenitor cell (HSPC) mobilization from the bone marrow in a cell-nonautonomous fashion. This process is mediated, in part, through suppression of osteoblasts and disruption of CXCR4/...

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Detalles Bibliográficos
Autores principales: Christopher, Matthew J., Rao, Mahil, Liu, Fulu, Woloszynek, Jill R., Link, Daniel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039862/
https://www.ncbi.nlm.nih.gov/pubmed/21282380
http://dx.doi.org/10.1084/jem.20101700