Cargando…
In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation
The introduction of non-natural entities into proteins by chemical modification has numerous applications in fundamental biological science and for the development and manipulation of peptide and protein therapeutics. The reduction of native disulfide bonds provides a convenient method to access two...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039925/ https://www.ncbi.nlm.nih.gov/pubmed/21271715 http://dx.doi.org/10.1021/bc1004685 |