Insight into a Novel p53 Single Point Mutation (G389E) by Molecular Dynamics Simulations

The majority of inactivating mutations of p53 reside in the central core DNA binding domain of the protein. In this computational study, we investigated the structural effects of a novel p53 mutation (G389E), identified in a patient with congenital adrenal hyperplasia, which is located within the ex...

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Detalles Bibliográficos
Autores principales: Pirolli, Davide, Alinovi, Cristiana Carelli, Capoluongo, Ettore, Satta, Maria Antonia, Concolino, Paola, Giardina, Bruno, De Rosa, Maria Cristina
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039947/
https://www.ncbi.nlm.nih.gov/pubmed/21339981
http://dx.doi.org/10.3390/ijms12010128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039947/
https://www.ncbi.nlm.nih.gov/pubmed/21339981
http://dx.doi.org/10.3390/ijms12010128

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