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RNA Interference Targeting Slug Increases Cholangiocarcinoma Cell Sensitivity to Cisplatin via Upregulating PUMA

Slug is an E-cadherin repressor and a suppressor of PUMA (p53 upregulated modulator of apoptosis) and it has recently been demonstrated that Slug plays an important role in controlling apoptosis. In this study, we examined whether Slug’s ability to silence expression suppresses the growth of cholang...

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Detalles Bibliográficos
Autores principales: Zhang, Kejun, Chen, Dong, Wang, Xingang, Zhang, Shaoyan, Wang, Jigang, Gao, Yuan, Yan, Bomin
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039959/
https://www.ncbi.nlm.nih.gov/pubmed/21339993
http://dx.doi.org/10.3390/ijms12010385