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In Silico Theoretical Molecular Modeling for Alzheimer’s Disease: The Nicotine-Curcumin Paradigm in Neuroprotection and Neurotherapy

The aggregation of the amyloid-β-peptide (AβP) into well-ordered fibrils has been considered as the key pathological marker of Alzheimer‘s disease. Molecular attributes related to the specific binding interactions, covalently and non-covalently, of a library of compounds targeting of conformational...

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Detalles Bibliográficos
Autores principales: Kumar, Pradeep, Pillay, Viness, Choonara, Yahya E., Modi, Girish, Naidoo, Dinesh, du Toit, Lisa C.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039975/
https://www.ncbi.nlm.nih.gov/pubmed/21340009
http://dx.doi.org/10.3390/ijms12010694